Background: Chronic kidney disease (CKD) is a growing health concern worldwide. Thyroid dysfunction is common in CKD patients, affecting disease progression and patient outcomes.Objectives: To determine the prevalence of thyroid disorders in CKD patients and explore relationships with age, gender, CKD staging, and comorbidities.Methods: The present study enrolled 135chronic kidney disease patients from L.N. Medical College and Research Centre & J.K. Hospital, Bhopal. Inclusion criteria consisted of CKD diagnosis, elevated blood urea and serum creatinine, reduced creatinine clearance, and ultrasonography evidence. Exclusion criteria included pre-existing thyroid disorders, medications affecting thyroid function, acute illness, and hemodialysis.Results: Normal thyroid function was observed in 48.1% of patients.Primary subclinical hypothyroidism (19.3%), non-thyroidal illness (12.6%), and clinical/overt hypothyroidism (8.9%) were common.CKD staging revealed stages 3 and 4 as most prevalent (31.11% each).Thyroid disorders were significantly associated with CKD stages (p-value 0.002). No significant association was found between thyroid disorders and age (p-value 0.346) or gender (p-value 0.845).Hypertension (109) and comorbidities (101) were highly prevalent.Conclusion: Thyroid dysfunction is common in CKD patients, with primary subclinical hypothyroidism and non-thyroidal illness being prevalent. CKD staging significantly correlates with thyroid disorders. Regular thyroid function monitoring is crucial in CKD patients across all age groups and genders.