Aim:This study aimed to evaluate cardiometabolic risk factors among obese pediatric patients aged 6–18 years and assess gender-based differences in anthropometric, clinical, laboratory, and lifestyle parameters. Material and Methods:A cross-sectional observational study was conducted over 12 months at a tertiary care hospital, including 100 obese pediatric patients aged 6–18 years (BMI ≥95th percentile). Data were collected on demographic details, anthropometric measurements (weight, height, BMI, waist circumference), clinical parameters (blood pressure, Tanner staging), laboratory investigations (fasting blood glucose, insulin, HbA1c, lipid profile), and lifestyle factors (screen time, physical activity). Cardiometabolic risk factors, including metabolic syndrome, insulin resistance, and hypertension, were assessed. Statistical analysis was performed using SPSS version 26.0, with a significance level of p<0.05. Results:No significant gender-based differences were observed in demographic parameters, anthropometric indices, blood pressure, fasting blood glucose, insulin levels, HbA1c, HDL, LDL, triglycerides, or lifestyle habits. Metabolic syndrome prevalence was comparable between females (33%) and males (28%), as were insulin resistance (43% in females vs. 38% in males) and hypertension (24% in females vs. 26% in males). These findings suggest an equal burden of cardiometabolic risk factors across genders. Conclusion:Cardiometabolic risk factors are evenly distributed among male and female obese pediatric patients. Early identification, regular screening, and comprehensive gender-neutral intervention strategies are essential for preventing long-term cardiometabolic complications associated with childhood obesity.