Background: Chronic liver disease is a common clinical problem in our country. In chronic liver disease, the liver parenchyma gradually deteriorates and regenerates, leading to cirrhosis and fibrosis. The present study was conducted to assess renal function in patients with chronic liver diseases. Materials & Methods:104 patients with chronic liver disease of both genders were selected. Aspartate amino transferase S, alanine amino transferase, alkaline phosphatase, total bilirubin with both conjugated and unconjugated fraction, total protein, albumin, globulin, prothrombin time, anti-nuclear antibody, and anti-liver kidney microsomal antibodies 1, 2, and 3 were among the many laboratory tests that were performed. Ascitic fluid was examined in order to ascertain the etiology and severity of chronic liver disease. Kidney function was assessed by measuring serum potassium, sodium, urea, and creatinine. Results: Out of 104 patients, 64 were males and 40 were females. Various liver diseases were alcoholic liver disease in 48, autoimmune hepatitis in 12, chronic Hepatitis- B in 32, and chronic Hepatitis- C in 12 patients. The difference was significant (P< 0.05). Serum albumin <3 gm/dl was seen in 62, 3-3.5 gm/dl in 13 and >3.5gm/dl in 29 patients. Serum globulin <2.5 gm/dl was seen in 76, 2.5-4 gm/dl in 14 and >4 gm/dl in 14 patients. Serum urea 15-40 mg/dl was seen in 86 and >40 mg/dl in 18 patients. Creatinine 1 mg/dl was seen in 89 and 2 mg/dl in 15 patients. The difference was significant (P< 0.05). Conclusion: The severity of liver dysfunction and some renal dysfunction measures have been discovered to be significantly correlated by the authors.