Original Articles
Epidemiological assessment of breast cancer patients and their association with ABO blood group: A cross-sectional study | |
Dr. Krishan Kumar, Dr. Ashok Kumar Gupta | |
Background: Breast cancer (BC) significantly affects the health of women globally and is recognized as one of the most prevalent forms of cancer. As a readily identifiable component of an individual's genetic profile, ABO blood groups have been statistically linked to various diseases. Hence; the present epidemiological study was conducted for assessing breast cancer patients and their association with ABO blood group. Materials & methods: A total of 560 breast cancer patients were screened for the present study. Another set of 560 age-matched healthy females were enrolled as control group. Complete demographic and clinical details of all the subjects was obtained. A Performa was made and detailed medical history of all subjects was recoded separately. Finger pricking was done and blood drop was obtained from all the subjects. ABO blood grouping was assessed in all the patients. Correaltion between blood grouping and breast cancer was done. All the results recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software Results:Mean age of the patients of the cases and controls was 39.2 years and 38.7 years respectively. among cases and controls, majority of the subjects were rural residence. Among cases, 212, 164, 96 and 88 subjects were of A blood group, B blood group, AB blood group and O blood group respectively. Among controls, 231, 151, 102 and 76 subjects were of A blood group, B blood group, AB blood group and O blood group respectively. Among cases and controls, 453 and 475 subjects were Rh+ respectively. Non-significant results were obtained while corralling blood grouping with breast cancer. Conclusion: ABO blood types represent a polymorphic and antigenic genetic system that is characterized by the presence of specific substances located on the surface of red blood cells (RBCs) as well as in various other cells and tissues. However; we didn’t observed any significant correlation of ABO blood grouping with occurrence of breast cancer. |
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