Aims and Objectives: To find out the incidence of adverse events following immunization (AEFIs) after COVID-19 vaccination. Material and Methods: This is a prospective study of the AEFIs associated with COVID-19 vaccine (Covishield) at the Government Medical College Anantnag. The volunteers after getting vaccinated were asked to wait in the ADR surveillance room of vaccination centre for at least 30 minutes for any immediate unexpected adverse reaction before leaving the vaccination centre. The demographic as well as other necessary health details were received and entered on a predesigned Covid-19 vaccine safety surveillance form (CVSSF) developed by the department of pharmacology, GMC Anantnag. These participants were telephonically called for any possible AEFI after the gap of 24 hours and 72 hours after receiving the vaccination dose (for both first and second dose). Results: A total of 1765 individuals got vaccinated whose mean age was 46.8 years ranging from17 years to 93 years out of which 38% were females and 62% were males. Total of 422 participants showed AEFI out of which 379 (49.8%) developed AEFI after first dose of vaccination while only 43 (7.4%) developed AEFI after 2nd dose of vaccination. The most common AEFI after first and 2nd dose of vaccine were fever, chills, local pain, fatigue and myalgia. None of the participants who developed the AEFI required hospitalization. Conclusion: We conclude that the AEFIs associated with COVID-19 vaccination are mostly mild and can be managed without hospitalization.