Original Articles
Comparison of Intrathecal Dexmedetomidinevs Fentanyl as Adjuvants to Hyperbaric Levobupivacaine in Infraumbilical Surgeries Under Spinal Anaesthesia | |
Srivastava Neha, Rai Sudhir K, Maurya Indubala, Maurya Ram G | |
Background: Various adjuvants have been reported to significantly enhance the quality of spinal anaesthesia. Aim & objective: To evaluate the effectiveness of Dexmedetomidine and Fentanyl as adjuvants to Hyperbaric Levobupivacaine 0.5% in enhancing the quality of spinal anaesthesia. Material & Methods: A total of 60 patients aged 18-65 were randomised into two groups ie. Group LD and Group LF, received 10 µg Dexmedetomidine and 25 µg Fentanyl respectively as adjuvants to 3 ml of 0.5% hyperbaric levobupivacaine. Time to achieve sensory and motor block, total duration of blocks, post-operative pain scores (VAS) and time to first rescue analgesia were recorded. Results: Time taken for onset of sensory and motor blocks was significantly longer in Group LF (3.02±0.55 min and 3.86±0.85 min, respectively) as compared to the Group LD(2.43±0.57 min and 3.35±0.56 min, respectively). However, the duration of sensory and motor block was significantly longer in Group LD (343.00±52.66 min and 338.00±52.22 min) compared to the LF group (213.00±33.75 min and 199.00±29.98 min, respectively). Duration of analgesia was also significantly prolonged in Group LD (366.90±52.02 min) compared to Group LF (232.77±33.77 min). Group LF had significantly higher mean pain scores as compared to that in Group LD at 4 hours and from 8 hours to 24 hr (p<0.05). Conclusion: Dexmedetomidine outperformed fentanyl to block quality but carried an increased risk of bradycardia. |
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