Introduction: Laparoscopic Cholecystectomy has become the standard treatment for symptomatic cholelithiasis. Despite the advances in the fields of antimicrobial agents, sterilization techniques, port site infections still prevail. These post-operative wound infections have an enormous impact on patient’s quality of life and contribute substantially to financial cost of patient care. The present prospective study was conducted to assess the incidence, risk factors and organism associated with surgical site infection in cases undergoing elective laparoscopic cholecystectomy in Shri Mahant Indiresh Hospital. Aim: The assessment of surgical site infections in patient undergoing elective laparoscopic cholecystectomy. Patient and methods: This prospective observational study was conducted in SMI hospital for period of 18 months. 100 patient were taken for study after informed written consent. The assessment of surgical site infection was done in these patients after following standard criteria. Results: The incidence of SSI was found in 6% cases included in study. SSI was higher in elderly, male gender, patients with DM and when operative time was more than 60 minutes. SSI was common in epigastric port. Staphylococcus aureus was the comment organism. Conclusion: Despite advances in minimal access surgery, surgical site infections can still be problematic in few cases, although incidence is less than in open surgeries.