Objective: To Evaluate The Correlation Between Positive Gastric Aspirate Cytology And Early Neonatal Sepsis; To Assess The Relationship Between Gastric Aspirate Cytology Results And Early Onset Neonatal Warning Signs. Methods: This Hospital-Based Prospective Study Was Conducted At The Department Of Pediatrics, Muzaffarnagar Medical College, Over 18 Months. The Study Included 45 Newborns Exhibiting Risk Factors For Sepsis. Gastric Aspirate Cytology Was Performed Before The First Feeding, And Its Results Were Correlated With Clinical Signs Of Sepsis And Laboratory Findings. Statistical Analysis Involved Chi-Square Tests For Categorical Data And T-Tests For Continuous Variables. Result And Conclusion: The Study Found That 46.7% Of The Gastric Aspirate Samples Tested Positive For Cytological Signs Of Infection. There Was A Significant Correlation Between Positive Gastric Aspirate Results And Confirmed Sepsis Cases. The Neonatal Early Warning Score Also Showed Significant Associations With Positive Cytology Results, Indicating Its Potential Utility In Predicting Sepsis.