Background:Globally, both men and women suffer from chronic obstructive pulmonary disease (COPD), a chronic lung condition that can be prevented and treated. The present study was conducted to assess determinants of chronic obstructive pulmonary disease. Materials & Methods:110 patients suspected of COPD of both genders were selected. Spirometry was performed using a Spirolab spirometer. Results:Out of 110 patients, 67 were males and 43 were females. Clinical features among COPD and non- COPD patients were chronic cough in 56% and 41%, chronic phlegm in 45% and 10%, wheezing episodes in past 12 months in 25% and 26%, shortness of breath in 81% and 62%, exacerbation in 43% and 30% and comorbidities among 54% and 50% respectively. The difference was significant (P< 0.05). Among COPD patients, 28 were in GOLD 1, 22 in GOLD 2, 6 in GOLD 3 and 4 in GOLD 4. 15 were non- smokers. Current smokers were 8, 13, 4 and 3 and ex- smokers were 5, 9, 2 and 3 having GOLD 1, GOLD 2, GOLD 3 and GOLD 4 respectively. Biomass index >100 were 14, 8, 3 and 1 having GOLD 1, GOLD 2, GOLD 3 and GOLD 4 respectively. The mean pack years was 15.2 years, 32.5 years, 35.8 years and 42.3 years having GOLD 1, GOLD 2, GOLD 3 and GOLD 4 respectively. The difference was significant (P< 0.05). Conclusion: Given that smoking is a major risk factor for developing COPD, there may be a rise in behavior modification and smoking cessation education at urban periphery healthcare facilities.