Background:Hydatid disease, a zoonotic infection caused by Echinococcus species, primarily affects the liver and lungs. The study aimed to analyze the demographic characteristics, clinical presentation, and treatment outcomes of patients diagnosed with hydatid disease.Material and Methods:This descriptive observational study was conducted at the Department of Surgery, LN Medical College, and JK Hospital, Bhopal, over 30 months. Twenty-two patients diagnosed with hydatid disease were included. Data were collected on demographics, clinical presentation, organ involvement, imaging findings, treatment modalities, and outcomes. Results:The mean age of the 22 patients was 37.5 ± 11.2 years, with males comprising 63.6%. Common comorbidities included diabetes mellitus (27.2%) and hypertension (18.2%). The liver was the most commonly involved organ (68.2%), followed by the lungs (27.3%) and spleen (4.5%). Most cysts were unilocular (CE1, 45.5%), with an average size of 8.6 ± 3.1 cm. Surgery was performed in 77.3% of cases, with a mean operative time of 85.4 ± 28.7 minutes. Postoperative complications were minimal (14.3%), with no recurrences observed.Conclusion:Hydatid disease predominantly affects the liver and lungs, requiring a multidisciplinary approach for diagnosis and treatment. Surgical intervention remains the cornerstone of management, complemented by antiparasitic therapy. Early diagnosis and tailored management strategies result in favorable outcomes.