Original Articles
Survival analysis of esophageal carcinoma patients: An observational study | |
Roja Kiran Gajula, K Vijay Kumar, Srinivas D, Jagadeesh Pavuluru | |
Background:The present study was conducted for evaluating survival analysis of esophageal carcinoma patients.Materials & methods:40 patients with presence of esophageal carcinoma were enrolled. A comprehensive treatment plan was developed, incorporating both radiation oncotherapy and surgical procedures. The outcomes of the treatment were assessed for all patients involved. A survival analysis was conducted to evaluate the distinct risk factors associated with mortality. All findings were documented in a Microsoft Excel spreadsheet and subsequently analyzed statistically using SPSS software. The Chi-square test and Student's t-test were employed to determine the significance levels. Additionally, univariate analysis was performed to assess the risk factors.Results:The average age of the patients was 49.7 years, with males constituting 80 percent of the cohort. A history of tobacco use was reported in 80 percent of the patients, while 72 percent had a history of alcohol consumption. Clinical staging revealed that 40 percent of the patients were classified as T3, and 20 percent as T4. The majority, 80 percent, were diagnosed with squamous cell carcinoma, whereas 20 percent had adenocarcinoma. The mortality rate observed was 13.33 percent. Significant risk factors linked to poor survival included older age, a history of alcohol consumption, tobacco smoking, and clinical stages III and IV.Conclusion:Esophageal carcinoma is a notable malignancy associated with a dismal prognosis, largely due to its diagnosis at an advanced stage. |
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